REGULATION OF MATING AND MEIOSIS IN YEAST BY THE MATING-TYPE REGION

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Regulation of mating and meiosis in yeast by the mating-type region.

A supposed sporulation-deficient mutation of Saccharomyces cerevisiae is found to affect mating in haploids and in diploids, and to be inseparable from the mating-type locus by recombination. The mutation is regarded as a defective a allele and is designated a*. This is confirmed by its dominance relations in diploids, triploids, and tetraploids. Tetrad analysis of tetraploids and of their spor...

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Regulation of fission yeast mating-type interconversion by chromosome imprinting.

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Yeast Mating Type

Saccharomyces cerevisiae, baker’s yeast, can exist in either a haploid (1n) or a diploid (2n) state. Haploids express one of two mating types, a or a (alpha). Haploids of either mating type are capable of mating with haploids of the opposite mating type in response to the action of mating pheromones. Mating results in fusion of haploid cells, forming an a/a diploid, which is no longer capable o...

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Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.

The ultimate product of yeast mating-type interconversion is a stable a/alpha diploid cell. A haploid cell carrying the HO gene gives rise to a diploid cell in a two-step process: first, the cell switches mating type as a result of genetic rearrangement (cassette substitution) catalyzed by HO; then, cells of opposite type mate to form a/alpha diploids. Mating-type interconversion does not occur...

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The mating-type proteins of fission yeast induce meiosis by directly activating mei3 transcription.

Cell type control of meiotic gene regulation in the budding yeast Saccharomyces cerevisiae is mediated by a cascade of transcriptional repressors, a1-alpha2 and Rme1. Here, we investigate the analogous regulatory pathway in the fission yeast Schizosaccharomyces pombe by analyzing the promoter of mei3, the single gene whose expression is sufficient to trigger meiosis. The mei3 promoter does not ...

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ژورنال

عنوان ژورنال: Genetics

سال: 1976

ISSN: 1943-2631

DOI: 10.1093/genetics/82.2.187